At least five people were killed, and five others hospitalized after an Amazon cargo plane overran a runway at Miami International Airport on Sunday, Sept. 6, striking multiple vehicles and erupting in flames, authorities said.
Prime Air Flight 7598 overran an airport diagonal runway just before 2 p.m. local time, Miami-Dade Sheriff Rosie Cordero-Stutz said during a news conference Sunday afternoon. The Federal Aviation Administration and Amazon confirmed the plane came down striking multiple vehicles.
According to Miami-Dade County fire officials, some victims were trapped inside the vehicles and at least three of the wounded are in critical condition.
“We will continue to update you as soon as information is confirmed,” Rosie Cordero-Stutz told reporters. “Our entire community is joined in prayers and grieving for those who are affected.”
Miami-Dade County Fire Chief Raied Jadallah said the aircraft is leaking fuel and officials are working to contain it. Authorities were not immediately sure what caused the crash, and Cordero-Stutz declined to answer additional questions from reporters.
The incident forced the closure of one of the nation’s busiest airports. All runways and taxiways are closed.
More than 60 Miami-Dade Fire Rescue units responded to the scene. The fire department said the plane struck multiple vehicles and is “assessing patients.” Officials did not immediately report on the condition of the people hospitalized.
A video of the crash obtained by NBC News Miami shows fire and a black cloud of smoke billowing from the aircraft. The FAA issued a ground stop at the airport until at least 5:30 p.m. ET and said it will investigate the incident.
Air Flight 7598, an Amazon Air Boeing 767-300 jet, had departed San Juan, Puerto Rico, earlier in the day Sept. 6. Transportation Secretary Sean Duffy said travelers using Miami International Airport should expect delays and potential cancellations.
“We’re working closely with local authorities and officials to understand exactly what happened,” Amazon told USA TODAY in a statement. “Right now, our absolute priority is the safety, well-being, and care of everyone involved.”
USA TODAY reached out to the flight’s operator, 21 Air, for comment.
Cargo plane crashes in the US
The crash is the latest in a series of high-profile aircraft accidents in the United States. In November 2025, a UPS cargo jet crashed shortly after takeoff from Louisville Muhammad Ali International Airport in Kentucky, killing 14.
The National Transportation Safety Board found that the left engine detached from the plane and caught fire, the USA TODAY Network previously reported.
In January 2025, an American Airlines regional jet collided with an Army Black Hawk helicopter near Reagan Washington National Airport, killing all 67 people aboard the two aircraft. NTSB members later said the crash resulted from a “multitude of errors” and “systemic issues across multiple organizations.”
This story has been updated to add new information.
This article originally appeared on USA TODAY: At least 5 dead after Amazon cargo plane crashed at Miami airport
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